Binap-Gold(I) versus Binap-Silver Trifluoroacetate Complexes as Catalysts in 1,3-Dipolar Cycloadditions of Azomethine Ylides

Binap-gold(I) versus Binap-silver trifluoroacetate complexes as catalysts in 1,3-dipolar cycloadditions of azomethine ylides.

The 1,3-dipolar cycloaddition between azomethine ylides and alkenes is efficiently catalysed by [{(S(a))-Binap-Au(tfa)}(2)] (Binap=2,2'-bis(diphenylphosphino)-1,1'-binaphthyl; tfa=trifluoroacetyl). Maleimides, 1,2-bis(phenylsulfonyl)ethylene, chalcone and nitrostyrene were suitable dipolarophiles even when using sterically hindered 1,3-dipole precursors. The results obtained in these transforma...

Catalytic Enantioselective 1,3-Dipolar Cycloadditions of Azomethine Ylides for Biology-Oriented Synthesis

Cycloaddition reactions are among the most powerful methods for the synthesis of complex compounds. In particular, the development and application of the 1,3-dipolar cycloaddition, an important member of this reaction class, has grown immensely due to its powerful ability to efficiently build various five-membered heterocycles. Azomethine ylides are commonly used as dipoles for the synthesis of...

Metal Complexes versus Organocatalysts in Asymmetric 1,3-Dipolar Cycloadditions

Asymmetric 1,3-dipolar cycloadditons of stabilized azomethine ylides with nitroalkenes.

This review highlights the biological importance of many polysubstituted nitro-prolines and -pyrrolidines. Their preparation using asymmetric 1,3-dipolar cycloadditions of azomethine ylides with nitroalkenes using diastereoselective and enantioselective strategies is described remarking the scope and main features of each one.

Complexes of Gold(I) with a Chiral Diphosphine Ligand: A Polymer with Both Au···Ag and Ag···Ag Metallophilic Bonds

Dedicated to Professor Hubert Schmidbaur, the grand master of gold chemistry, on the occasion of his 75th birthday The chemistry of gold(I) with the ligand binap = 2,2′-bis(diphenylphosphino)-1,1′ -binaphthyl is reported. Reaction of [Au2Cl2(μ-binap)] with silver trifluoroacetate gave the corresponding complex [Au2(O2CCF3)2(μ-binap)], and crystallization in the presence of excess silver trifluo...